228 top medical experts on Protein S Deficiency across 36 countries and 8 U.S. states, including 77 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants.
- Protein S Deficiency: An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. protein S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated protein C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)
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- Broader Categories (#Experts): Blood Coagulation Disorders (2,664), Blood Protein Disorders (103), Thrombophilia (2,217).
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