984 top medical experts on Hereditary Nonpolyposis Colorectal Neoplasms across 51 countries and 39 U.S. states, including 899 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants.
- Hereditary Nonpolyposis Colorectal Neoplasms: A group of autosomal-dominant inherited diseases in which colon cancer arises in discrete adenomas. Unlike familial polyposis coli with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. hnpcc has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and lynch syndrome II which includes extracolonic cancer.
- Clinical guidelines are the recommended starting point to understand initial steps and current protocols in any disease or procedure:
- Guideline Central: American Medical Association (1, 2)
- UK NICE Guidelines: Molecular testing strategies for Lynch syndrome in people with colorectal cancer
- NCCN guidelines (login required)
- PubMed Practice Guideline
- U.S. National Guideline Center (archived)
- Broader Categories (#Experts): Hereditary Neoplastic Syndromes (1,826), DNA Repair-Deficiency Disorders (751), Colorectal Neoplasms (4,574) and Narrower Categories: Lynch Syndrome II (130).
- Clinical Trials : at least 89 including 8 Active, 26 Completed, 32 Recruiting
- Synonyms: Type 1 Familial Nonpolyposis Colon Cancer, Type 1 Hereditary Nonpolyposis Colorectal Cancer, Familial Nonpolyposis Colon Cancer Type 1, Hereditary Nonpolyposis Colorectal Cancer, Hereditary Nonpolyposis Colorectal Cancer Type 1, Lynch Syndrome
Computing Expert Listing ...