205 top medical experts on Canavan Disease across 23 countries and 13 U.S. states, including 29 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants.

  1. Canavan Disease: A rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolization and demeylination that gives rise to a spongy appearance. Aspartoacylase deficiency leads to an accumulation of N-acetylaspartate in astrocytes. Inheritance may be autosomal recessive or the illness may occur sporadically. This illness occurs more frequently in individuals of Ashkenazic Jewish descent. The neonatal form features the onset of hypotonia and lethargy at birth, rapidly progressing to coma and death. The infantile form features developmental delay, dyskinesias, hypotonia, spasticity, blindness, and megalencephaly. The juvenile form is characterized by ataxia; optic atrophy; and dementia. (From Adams et al., Principles of Neurology, 6th ed, p944; Am J Med Genet 1988 Feb;29(2):463-71)
  2. Clinical guidelines are the recommended starting point to understand initial steps and current protocols in any disease or procedure:
  3. Broader Categories (#Experts): Hereditary Central Nervous System Demyelinating Diseases (1,644), Nervous System Heredodegenerative Disorders (865).
  4. Clinical Trials ClinicalTrials.gov : at least 9 including 2 Completed, 2 Recruiting


  

        

                    


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