300 top medical experts on Tonic-Clonic Epilepsy across 52 countries and 22 U.S. states, including 168 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants.
- Tonic-Clonic Epilepsy: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
- Clinical guidelines are the recommended starting point to understand initial steps and current protocols in any disease or procedure:
- Broader Categories (#Experts): Generalized Epilepsy (1,214).
- Clinical Trials
: at least 9 including 1 Active, 6 Completed
- Synonyms: Grand Mal Epilepsy, Major Epilepsy, Grand Mal Seizure Disorder, Major Motor Seizure Disorder, Tonic Clonic Seizure Disorder
- Sperling, Michael R NeurologyDepartment of Neurology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, U.S.A.Medical school: Temple University School of Medicine (MD, 1978)Medicare AcceptedDisclosed payments in 2021 from 2 biomedical companies, totalling $1,920.33, including $1,320.33 from Biogen, Inc.Subjects: Epilepsy, Tonic-Clonic; Epilepsy, Temporal Lobe; Anticonvulsants; Drug Resistant Epilepsy; Diazepam; ElectromyographyCategories: Drug Therapy; Therapeutic Use; Complications; Methods; Diagnosis; Etiology
- Tatum, William O NeurologyDepartment of Neurology, Mayo Clinic, Jacksonville, Florida, U.S.A. Top HospitalDisclosed payments in 2021 from 2 biomedical companies, totalling $170, including $170 from Zimmer Biomet Holdings, Inc.Subjects: Epilepsy, Tonic-Clonic; Epilepsy, Generalized; Electromyography; Hand; Monitoring, Ambulatory; PostureCategories: Physiopathology; Methods; Pathology; Diagnosis; Physiology
- Siegel, Jason L Critical Care MedicineJacksonville, FL.Physician Highly PublishedSubjects: Epilepsy, Tonic-Clonic; Epilepsy, Generalized; Seizures; Hand; PostureCategories: Physiopathology; Pathology; Physiology
- Seyal, Masud NeurologyDepartment of Neurology, University of California, Davis, Sacramento, California, , U.S.A. Top HospitalPhysician Highly PublishedSubjects: Epilepsy, Tonic-Clonic; Respiration Disorders; Arrhythmias, Cardiac; Brain Waves; Electroencephalography; Epilepsy, Partial, MotorCategories: Complications; Etiology; Epidemiology; Physiopathology; Methods; Physiology
- French, Jacqueline A NeurologyDepartment of Neurology, New York University Comprehensive Epilepsy Center, New York, New York, U.S.A.Physician Clinical TrialDisclosed payments in 2021 from 8 biomedical companies, totalling $13,968.5, including $6,600 from UCB SASubjects: Epilepsy, Tonic-Clonic; Anticonvulsants; Electromyography; Monitoring, AmbulatoryCategories: Methods; Diagnosis; Drug Therapy; Physiopathology; Therapeutic Use
- Dlugos, Dennis J PediatricsDepartments of Neurology and Pediatrics, Childrens Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.Physician Clinical TrialDisclosed payments in 2021 from 14 biomedical companies, totalling $18,595.99, including $4,250 from GW Research LimitedSubjects: Epilepsy, Tonic-Clonic; Electromyography; Epilepsy, Absence; Monitoring, AmbulatoryCategories: Epidemiology; Methods; Diagnosis; Physiopathology
- Osorio, Ivan NeurologyDepartment of Neurology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA. Electronic address: .PhysicianDisclosed payments in 2021 from 4 biomedical companies, totalling $13,097,447.89, including $13,097,447.89 from LivaNova USA, Inc.Subjects: Deep Brain Stimulation; Electrodes; Electroencephalography; Epilepsy, Tonic-Clonic; ThalamusCategories: Instrumentation; Methods; Physiology; Therapy
- Morgan, Lola C NeurologyDepartment of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, U.S.A.Physician Clinical TrialMedical school: Loyola University of Chicago, Stritch School of Medicine (MD, 2000)Medicare Accepted; Medicare MIPS (Merit-based Incentive Payment System) rating: 58/100Disclosed payments in 2021 from 2 biomedical companies, totalling $29.53, including $16.93 from AQUESTIVE THERAPEUTICS, INC.Subjects: Epilepsy, Tonic-Clonic; Electromyography; Algorithms; Monitoring, Ambulatory; SeizuresCategories: Diagnosis; Methods; Physiopathology
- Moseley, Brian D NeurologyDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: .Physician Clinical TrialDisclosed payments in 2021 from 7 biomedical companies, totalling $6,144.88, including $3,894.88 from Eisai Inc.Subjects: Epilepsy, Tonic-Clonic; Anticonvulsants; Cerebral Cortex; Cerebrovascular Circulation; Drug Resistant Epilepsy; OxygenCategories: Drug Therapy; Blood; Therapeutic Use; Blood Supply; Pathology; Physiology
- Powers, Alexander K Neurological SurgeryWake Forest School of Medicine, Department of Neurosurgery, Winston Salem, NC, USA.Physician Case ReportsDisclosed payments in 2021 from 58 biomedical companies, totalling $117,407.21, including $78,649.42 from Stryker CorporationSubjects: Epilepsy, Tonic-Clonic; Brain; Brain Neoplasms; Hemispherectomy; Palliative Care; PseudolymphomaCategories: Diagnosis; Surgery; Methods
- Cavazos, Jose E NeurologyBrain Sentinel, San Antonio, TX, United States of America; University of Texas Health Science Center at San Antonio, San Antonio, TX, United States of America. Electronic address: .Physician Clinical TrialSubjects: Epilepsy, Tonic-Clonic; Caregivers; Electroencephalography; Electromyography; Hospital Units; Monitoring, AmbulatoryCategories: Diagnosis; Statistics & Numerical Data; Methods; Standards; Physiopathology
- Lie, Octavian V NeurologyDepartment of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, U.S.A.Physician Clinical TrialSubjects: Epilepsy, Tonic-Clonic; Electromyography; Algorithms; Monitoring, Ambulatory; SeizuresCategories: Diagnosis; Methods; Physiopathology
- Kennedy, Jeffrey D NeurologyDepartment of Neurology, University of California, Davis, Sacramento, California, , U.S.A. Top HospitalPhysicianSubjects: Epilepsy, Tonic-Clonic; Respiration Disorders; Arrhythmias, Cardiac; Electroencephalography; Epilepsy, Partial, Motor; HypoxiaCategories: Complications; Epidemiology; Etiology; Physiopathology; Methods
- Devinsky, Orrin NeurologyComprehensive Epilepsy Center, Department of Neurology, NYU Langone Medical Center, USA.Physician Case ReportsMedical school: Harvard Medical School (MD, 1982)Medicare Accepted; Medicare MIPS (Merit-based Incentive Payment System) rating: 86/100Disclosed payments in 2021 from 4 biomedical companies, totalling $59.73, including $31 from Eisai Inc.Subjects: Anticonvulsants; Epilepsy, Tonic-Clonic; Pyridones; Attention Deficit Disorder with Hyperactivity; Cognition Disorders; Memory DisordersCategories: Etiology; Adverse Effects; Therapeutic Use; Antagonists & Inhibitors; Complications; Drug Therapy
- Rutka, James T Neurological SurgeryPhysician Case ReportsDisclosed payments from biomedical company (Monteris Medical Corporation) in 2021 for $1,300Subjects: Epilepsy, Tonic-Clonic; Brain; Cortical Synchronization; Epilepsies, Myoclonic; Epilepsy, Frontal Lobe; Frontal LobeCategories: Physiopathology; Surgery; Methods
- Halford, Jonathan J NeurologyDepartment of Neurology, Medical University of South Carolina, Charleston, South Carolina, U.S.A.Physician Clinical TrialMedical school: Medico Chirurgical College of Philadelphia (MD, 1996)Medicare AcceptedDisclosed payments in 2021 from 2 biomedical companies, totalling $141.48, including $141.48 from SK Life Science, Inc.Subjects: Epilepsy, Tonic-Clonic; Electromyography; Monitoring, AmbulatoryCategories: Methods; Diagnosis; Physiopathology
- Lhatoo, Samden D NeurologyThe Center for SUDEP Research, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.PhysicianDisclosed payments in 2021 from 24 biomedical companies, totalling $969.71, including $517.79 from SK Life Science, Inc.Subjects: Epilepsy, Tonic-Clonic; Brain; Epilepsy, Generalized; Hypoxia; Movement; SeizuresCategories: Diagnosis; Metabolism; Diagnostic Imaging; Physiology
- Marson, Anthony GDepartment of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.Subjects: Epilepsy, Tonic-Clonic; Anticonvulsants; Epilepsies, Partial; Carbamazepine; Phenytoin; TriazinesCategories: Therapeutic Use; Drug Therapy; Analogs & Derivatives; Complications; Etiology
- Tudur, Smith CatrinDepartment of Biostatistics, University of Liverpool, Block F, Waterhouse Building, 1-5 Brownlow Hill, Liverpool, UK, L69 3GL.Subjects: Anticonvulsants; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Carbamazepine; Phenytoin; TriazinesCategories: Therapeutic Use; Drug Therapy; Analogs & Derivatives
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