311 top medical experts on Multiple Endocrine Neoplasia Type 2a across 44 countries and 21 U.S. states, including 172 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants.
- Multiple Endocrine Neoplasia Type 2a: A form of multiple endocrine neoplasia characterized by the presence of medullary carcinoma (carcinoma, medullary) of the thyroid gland, and usually with the co-occurrence of pheochromocytoma, producing calcitonin and adrenaline, respectively. Less frequently, it can occur with hyperplasia or adenoma of the parathyroid glands. This disease is due to gain-of-function mutations of the MEN2 gene on chromosome 10 (Locus: 10q11.2), also known as the RET proto-oncogene that encodes a receptor protein-tyrosine kinase. It is an autosomal dominant inherited disease.
- Clinical guidelines are the recommended starting point to understand initial steps and current protocols in any disease or procedure:
- Broader Categories (#Experts): Multiple Endocrine Neoplasia (574).
- Clinical Trials : at least 7 including 1 Active, 3 Completed, 2 Recruiting
- Synonyms: MEN 2, MEN 2a, Multiple Endocrine Type 2a Neoplasia, Multiple Endocrine Type 2a Neoplasms, Sipple Syndrome
- Waguespack, Steven G Pediatric EndocrinologyDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas.Disclosed payments in 2021 from 4 biomedical companies, totalling $9,360, including $9,360 from Bayer HealthCare Pharmaceuticals Inc.Subjects: Thyroid Neoplasms; Carcinoma, Medullary; Proto-Oncogene Proteins c-ret; Carcinoma, Neuroendocrine; ThyroidectomyCategories: Genetics; Therapy; Mortality; Surgery; Therapeutic Use; Congenital
- Gagel, Robert F Endocrinology, Diabetes & MetabolismDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030.Subjects: Thyroid Neoplasms; Proto-Oncogene Proteins c-ret; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Adrenal Gland NeoplasmsCategories: Genetics; Mortality; Therapy; Congenital; Methods; Diagnosis
- Evans, Douglas B Surgical OncologyDepartment of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.Subjects: Thyroid Neoplasms; Carcinoma, Medullary; Thyroidectomy; Antineoplastic Combined Chemotherapy Protocols; CalcitoninCategories: Surgery; Therapy; Diagnosis; Methods; Blood; Congenital
- Asa, Sylvia L Anatomic PathologyDepartment of Pathology, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, 44106, USA. Top HospitalPhysician GuidelineDisclosed payments in 2021 from 4 biomedical companies, totalling $1,312.5, including $1,312.5 from LEICA MICROSYSTEMS INC.Subjects: Thyroid Neoplasms; Adenocarcinoma, Follicular; Carcinoma, Medullary; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, NeuroendocrineCategories: Genetics; Pathology; Therapy; Congenital; Methods; Therapeutic Use
- Grubbs, Elizabeth G Surgical OncologyDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, FCT 17.6000, Houston, TX 77030, USA.Medical school: Duke University School of Medicine (MD, 1999)Medicare Accepted; Medicare MIPS (Merit-based Incentive Payment System) rating: 68/100Subjects: Thyroid Neoplasms; Proto-Oncogene Proteins c-ret; Multiple Endocrine Neoplasia Type 1; Carcinoma, Medullary; ThyroidectomyCategories: Genetics; Psychology; Surgery; Diagnosis; Methods; Blood
- Perrier, Nancy D Surgical OncologyDepartment of Surgical Oncology, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030.Physician Highly PublishedMedical school: Louisiana State University School of Medicine In New Orleans (MD, 1993)Medicare Accepted; Medicare MIPS (Merit-based Incentive Payment System) rating: 68/100Subjects: Thyroid Neoplasms; Carcinoma, Medullary; Proto-Oncogene Proteins c-ret; Adenomatous Polyposis Coli; CalcitoninCategories: Genetics; Psychology; Surgery; Therapy; Diagnosis; Blood
- Widemann, Brigitte C Pediatric Hematology-OncologyPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Clinical Center, National Institutes of Health, Bethesda, Maryland, DC, USA.Physician Case ReportsSubjects: Adrenocortical Carcinoma; Carcinoma, Medullary; Colorectal Neoplasms, Hereditary Nonpolyposis; MutS Homolog 2 Protein; PiperidinesCategories: Genetics; Drug Therapy; Therapeutic Use; Congenital
- Lodish, Maya Pediatric EndocrinologyDevelopmental Endocrine Oncology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, Bethesda, Maryland.PhysicianSubjects: Carcinoma, Medullary; Piperidines; Proto-Oncogene Proteins c-ret; Quinazolines; Thyroid NeoplasmsCategories: Drug Therapy; Genetics; Therapeutic Use; Congenital
- Raue, FriedhelmEndocrine Practice Heidelberg, Molecular Genetic Laboratory, D-69120 Heidelberg, Germany.Subjects: Thyroid Neoplasms; Proto-Oncogene Proteins c-ret; Carcinoma, Neuroendocrine; Multiple Endocrine Neoplasia Type 2b; Carcinoma, MedullaryCategories: Genetics; Diagnosis; Pathology; Epidemiology; Congenital; Methods
- Frank-Raue, KarinEndocrine Practice Heidelberg, Molecular Genetic Laboratory, D-69120 Heidelberg, Germany.Subjects: Thyroid Neoplasms; Proto-Oncogene Proteins c-ret; Carcinoma, Neuroendocrine; Multiple Endocrine Neoplasia Type 2b; Carcinoma, MedullaryCategories: Genetics; Diagnosis; Pathology; Epidemiology; Congenital; Methods
- Pacini, FurioSection of Endocrinology and Metabolism, Department of Internal Medicine, Endocrinology and Metabolism and Biochemistry, University of Siena, Policlinico Santa Maria alle Scotte, Siena, Italy.Subjects: Carcinoma, Medullary; Thyroid Neoplasms; Proto-Oncogene Proteins c-ret; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, NeuroendocrineCategories: Genetics; Therapy; Congenital; Methods; Therapeutic Use
- Elisei, RossellaDepartment of Clinical and Experimental Medicine, Unit of Endocrinology University of Pisa, 56124 Pisa, Italy.Subjects: Carcinoma, Medullary; Thyroid Neoplasms; Proto-Oncogene Proteins c-ret; Carcinoma, Neuroendocrine; Germ-Line MutationCategories: Genetics; Congenital; Pathology; Therapy; Surgery; Methods
- Wells, Samuel AGenetics BranchNational Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA .Subjects: Carcinoma, Medullary; Thyroid Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Parathyroid GlandsCategories: Therapy; Congenital; Genetics; Methods; Surgery; Therapeutic Use
- Dralle, HenningDepartment of Visceral, Vascular and Endocrine Surgery, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle Saale, Germany.Subjects: Thyroid Neoplasms; Carcinoma, Medullary; Proto-Oncogene Proteins c-ret; Adrenal Gland Neoplasms; Germ-Line MutationCategories: Genetics; Congenital; Diagnosis; Methods; Pathology; Therapy
- Machens, AndreasDepartment of Visceral, Vascular and Endocrine Surgery, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle Saale, Germany.Subjects: Thyroid Neoplasms; Carcinoma, Medullary; Proto-Oncogene Proteins c-ret; Adrenal Gland Neoplasms; Germ-Line MutationCategories: Genetics; Congenital; Diagnosis; Methods; Pathology; Therapy
- Baloch, Zubair W Anatomic Pathology & Clinical PathologyDepartment of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA. Top HospitalPhysicianSubjects: Carcinoma, Medullary; Thyroid Neoplasms; Carcinoma, Neuroendocrine; Cell Proliferation; High-Throughput Nucleotide SequencingCategories: Genetics; Pathology; Congenital; Methods
- Schlumberger, MartinGustave Roussy, Laboratoire de Pathologie Expérimentale, F-94800 Villejuif, France.Subjects: Carcinoma, Medullary; Proto-Oncogene Proteins c-ret; Thyroid Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, NeuroendocrineCategories: Genetics; Therapy; Congenital; Methods; Pathology; Therapeutic Use
- Chen, Herbert SurgeryEndocrine Surgery Research Laboratory, The University of Wisconsin Carbone Cancer Center, Madison, WI, USA.Physician Highly PublishedSubjects: Thyroid Neoplasms; Carcinoma, Medullary; Thyroidectomy; Cell Cycle; Cyclin-Dependent Kinase 5Categories: Genetics; Congenital; Metabolism; Pathology; Surgery
- Moley, Jeffrey F*Department of Surgery, Washington University School of Medicine, St. Louis, MO †Department of Surgery, UT Southwestern, Dallas, TX ‡Department of Surgery, Scott and White Medical Center, Temple, TX §Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.Subjects: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Early Detection of CancerCategories: Therapy; Diagnosis; Complications; Congenital; Methods; Surgery
- Glod, John W Pediatric Hematology-OncologyPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Clinical Center, National Institutes of Health, Bethesda, Maryland, DC, USA.Subjects: Thyroid Neoplasms; Carcinoma, Neuroendocrine; Piperidines; Proto-Oncogene Proteins c-ret; QuinazolinesCategories: Drug Therapy; Genetics; Therapeutic Use; Therapy; Antagonists & Inhibitors; Complications
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