122 top medical experts on Mitochondrial Complex III Deficiency across 12 countries and 3 U.S. states, including 12 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants.

  1. Mitochondrial Complex III Deficiency: Mitochondrial complex III deficiency is one of several conditions caused by dysfunction of mitochondria , which are specialized compartments in cells that generate more than 90% of the energy required by the body.It is a severe, multisystem disorder that includes features such as lactic acidosis , hypotonia , hypoglycemia , failure to thrive , encephalopathy , and delayed psychomotor development. Involvement of internal organs , including liver disease and renal tubulopathy, may also occur. Symptoms typically begin at birth. Many affected individuals die in early childhood, but some have survived longer. It is generally caused by mutations in nuclear DNA in the BCS1L , UQCRB and UQCRQ genes and inherited in an autosomal recessive manner. However, it may also be caused by mutations in mitochondrial DNA in the MTCYB gene, which is passed down maternally or occurs sporadically and may result in a milder form of the condition.Treatment generally focuses on alleviating symptoms and/or slowing down the progression of the disease, and effectiveness can vary among individuals.
  2. Clinical guidelines are the recommended starting point to understand initial steps and current protocols in any disease or procedure:
  3. Support Organizations

Organizations Providing General Support


  

        

                    


    Computing Expert Listing ...