201 top medical experts on Mannose-Binding Protein Deficiency across 22 countries and 8 U.S. states, including 27 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants.
- Mannose-Binding Protein Deficiency: Mannose-binding lectin (MBL) deficiency results in a decreased amount of a specific protein (mannan-binding protein) involved in the immune system . It was originally thought that MBL deficiency resulted in an increased susceptibility to infections . However, low levels of this protein have been found in many healthy people.MBL deficiency is more likely to be associated with infections in toddlers and those who have a weakened immune system (immunocompromised), including those with an underlying medical condition, cancer patients undergoing chemotherapy , and organ-transplant patients .Some studies have also suggested an association between severe MBL deficiency and recurrent infections.MBL deficiency is caused by changes in the MBL2 gene . However, it is important to note that changes in this gene are very common in the general population.Treatment for individuals with recurrent infections and MBL deficiency may include antibiotics to treat bacterial infections and regular vaccinations . Prophylactic antibiotics may be indicated in some cases.
- Clinical guidelines are the recommended starting point to understand initial steps and current protocols in any disease or procedure:
- Support Organizations
- Immune Deficiencies Foundation Australia
PO Box 969
Penrith NSW 2751
Australia
Telephone: 800-100-198
E-mail: info@idfa.org.au
Website: http://www.idfa.org.au/
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Organizations Providing General Support
- Autoimmune Association
19176 Hall Road, Suite 130
Clinton Township, MI 48038
Telephone: 586-776-3900
E-mail: hello@autoimmune.org
Website: https://autoimmune.org/
- Immune Deficiency Foundation
110 West Road, Suite 300
Towson, MD 21204
Toll-free: 1-800-296-4433
Fax: +1-410-321-9165
E-mail: https://www.primaryimmune.org/services/ask-idf/
Website: https://www.primaryimmune.org/
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