206 top medical experts on Heavy Chain Disease across 17 countries and 10 U.S. states, including 66 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants.

  1. Heavy Chain Disease: A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the N-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (V) and constant (C) region genes.
  2. Clinical guidelines are the recommended starting point to understand initial steps and current protocols in any disease or procedure:
  3. Broader Categories (#Experts): Lymphoproliferative Disorders (2,703), Paraproteinemias (1,357) and Narrower Categories: Immunoproliferative Small Intestinal Disease (89).
  4. Synonyms: Franklin Disease,  gamma-Chain Disease,  mu-Chain Disease


  

        

                    


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